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Neoplastic Characteristics of the DNA Found in the Plasma of Cancer Patients

1989; Karger Publishers; Volume: 46; Issue: 5 Linguagem: Inglês

10.1159/000226740

1423-0232

Maurice Stroun, Philippe Anker, P Maurice, Jacqueline Lyautey, C Lederrey, Mirko Beljanski,

Cancer Genomics and Diagnostics

About one third of patients with various malignant diseases were found to have extractable amounts of DNA in their plasma whereas no DNA could be detected in normal controls. Using the test established by one of us (M.B.), which is based on decreased strand stability of cancer cell DNA, we have found that several plasma DNA originate from cancer cells.