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Unique Monoterpenoid Indole Alkaloids from Alstonia scholaris

2007; American Chemical Society; Volume: 9; Issue: 9 Linguagem: Inglês

10.1021/ol0705301

1523-7060

Xiang‐Hai Cai, Zhi‐Zhi Du, Xiao‐Dong Luo,

Traditional and Medicinal Uses of Annonaceae

A pair of geometrically isomeric monoterpenoid indole alkaloids with a skeleton rearrangement and two additional carbons, named (19,20) E-alstoscholarine (1) and (19,20) Z-alstoscholarine (2), were obtained from the leaf extract of Alstonia scholaris. Their structures were elucidated on the basis of spectroscopic methods and then confirmed by X-ray crystal diffraction. The biogenesis of these compounds was also proposed.