Artigo Acesso aberto Revisado por pares

Song: Enzymes speed reactions (to the tune of “we will rock you,” by queen)*S

2006; Wiley; Volume: 34; Issue: 4 Linguagem: Inglês

10.1002/bmb.2006.494034042647

ISSN

1539-3429

Autores

P. Andrew Karplus,

Tópico(s)

Origins and Evolution of Life

Resumo

Michaelis and Menton did a lot o' diggin' to get the rate equation for an enzyme. “V” is Vmax:[S] ova' [S] plus Km; starts out steep and it flattens out then, singin' Enzymes speed reactions; enzymes speed reactions Transition state recognition is the key 'cuz it lowers activation free energy. Yo! how much substrate gives half the best rate is how we find Km on any ol' date, singin' Enzymes speed reactions; enzymes speed reactions Competitive inhibitors raise the Km but the Vmax always stays just the same. Noncompetitive's the other way round, with the Km unchanged and the Vmax goin' down, singin' Enzymes speed reactions; enzymes speed reactions You're in college now make a big noise learnin' all 'bout enzymes taught in Biochemistry. You got facts in yo' head, just what the Prof said, spreadin' out yo' notes all over the bed, dreamin' Enzymes speed reactions; enzymes speed reactions

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