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Why an Alternative to Blood Transfusion?

2009; Elsevier BV; Volume: 25; Issue: 2 Linguagem: Inglês

10.1016/j.ccc.2008.12.012

1557-8232

Aryeh Shander, Lawrence T. Goodnough,

Hemoglobin structure and function

Allogeneic blood transfusions have been associated with several risks and complications and with worse outcomes in a substantial number of patient populations and clinical scenarios. Allogeneic blood is costly and difficult to procure, transport, and store. Global and local shortages are imminent. Alternatives to transfusion provide many advantages, and their use is likely to improve outcomes as safer and more effective agents are developed.