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Synthesis, conformational analysis, and antiarrhythmic properties of 7-benzyl-3-thia-7-azabicyclo[3.3.1]nonan-9-one, 7-benzyl-3-thia-7-azabicyclo[3.3.1]nonane hydroperchlorate, and 7-benzyl-9-phenyl-3-thia-7-azabicyclo[3.3.1]nonan-9-ol hydroperchlorate and derivatives. Single-crystal x-ray diffraction analysis and evidence for chair-chair and chair-boat conformers in the solid state

1984; American Chemical Society; Volume: 27; Issue: 6 Linguagem: Inglês

10.1021/jm00372a010

1520-4804

Bruce R. Bailey, K. Darrell Berlin, Elizabeth M. Holt, Benjamin J. Scherlag, Ralph Lazzara, Johannes Brachmann, Dick Van der Helm, Douglas R. Powell, Nantelle S. Pantaleo, Peter C. Ruenitz,

Computational Drug Discovery Methods

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis, conformational analysis, and antiarrhythmic properties of 7-benzyl-3-thia-7-azabicyclo[3.3.1]nonan-9-one, 7-benzyl-3-thia-7-azabicyclo[3.3.1]nonane hydroperchlorate, and 7-benzyl-9-phenyl-3-thia-7-azabicyclo[3.3.1]nonan-9-ol hydroperchlorate and derivatives. Single-crystal x-ray diffraction analysis and evidence for chair-chair and chair-boat conformers in the solid stateBruce R. Bailey III, K. Darrell Berlin, Elizabeth M. Holt, Benjamin J. Scherlag, Ralph Lazzara, Johannes Brachmann, Dick Van der Helm, Douglas R. Powell, Nantelle S. Pantaleo, and Peter C. RuenitzCite this: J. Med. Chem. 1984, 27, 6, 758–767Publication Date (Print):June 1, 1984Publication History Published online1 May 2002Published inissue 1 June 1984https://pubs.acs.org/doi/10.1021/jm00372a010https://doi.org/10.1021/jm00372a010research-articleACS PublicationsRequest reuse permissionsArticle Views197Altmetric-Citations36LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts