Effects of Thyrotropin-Releasing Hormone and Metoclopramide in Patients with Phenothiazine-Induced Hyperprolactinemia*
1981; Oxford University Press; Volume: 53; Issue: 1 Linguagem: Inglês
10.1210/jcem-53-1-109
ISSN1945-7197
AutoresHarvey V. Lankford, William G. Blackard, DAVID F. GARDNER, Henry St. George Tucker,
Tópico(s)Pituitary Gland Disorders and Treatments
ResumoTRH and metoclopramide tests were performed in 10 female patients with presumed phenothiazine-induced hyperprolactinemia to define the serum PRL response to these agents. Our results show that the serum PRL response to metoclopramide is blunted in most patients with phenothiazine-induced hyperprolactinemia, and the serum PRL response to TRH is exaggerated in most patients during and 3 weeks after stopping phenothiazines.
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