Portal de Periódicos da CAPES

The CLIPMERGE PGx Program: Clinical Implementation of Personalized Medicine Through Electronic Health Records and Genomics–Pharmacogenomics

2013; Wiley; Volume: 94; Issue: 2 Linguagem: Inglês

10.1038/clpt.2013.72

1532-6535

Omri Gottesman, Stuart A. Scott, Stephen B. Ellis, Casey Lynnette Overby, A. Ludtke, Jean‐Sébastien Hulot, Jennifer L. Hall, Kimiharu Chatani, Kristin Myers, Joseph Kannry, Erwin P. Böttinger,

Pharmaceutical studies and practices

The exponential rise in genomics research over the past decade has yielded a growing number of sequence variants associated with medication response that may have clinical utility. Despite existing barriers, attention is turning to strategies that integrate these data into clinical care. The CLIPMERGE PGx Program is establishing a best-practices infrastructure for the implementation of genome-informed prescribing using a biobank-derived clinical cohort, preemptive genetic testing, and real-time clinical decision support deployed through the electronic health record. Clinical Pharmacology & Therapeutics (2013); 94 2, 214–217. doi:10.1038/clpt.2013.72