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GENITAL PLUS AUDIOVISUAL SEXUAL STIMULATION FOLLOWING INTRACAVERNOUS VASOACTIVE INJECTION VERSUS RE-DOSING FOR ERECTILE DYSFUNCTION-RESULTS OF A PROSPECTIVE STUDY

1998; Lippincott Williams & Wilkins; Volume: 159; Issue: 1 Linguagem: Inglês

10.1016/s0022-5347(01)64029-1

1527-3792

Francesco Montorsi, Giorgio Guazzoni, Luigi Barbeiri, Luigi Ferini‐Strambi, Sandro Iannaccone, Giliola Calori, Luciano Nava, P. Rigatti, G. Pizzini, A Miani,

Urinary Bladder and Prostate Research

No AccessJournal of UrologyClinical Urology: Original Articles1 Jan 1998GENITAL PLUS AUDIOVISUAL SEXUAL STIMULATION FOLLOWING INTRACAVERNOUS VASOACTIVE INJECTION VERSUS RE-DOSING FOR ERECTILE DYSFUNCTION-RESULTS OF A PROSPECTIVE STUDY Francesco Montorsi, Giorgio Guazzoni, Luigi Barbeiri, Luigi Ferini-Strambi, Sandro Iannaccone, Giliola Calori, Luciano Nava, Patrizio Rigatti, Giuliano Pizzini, and Alberto Miani Francesco MontorsiFrancesco Montorsi , Giorgio GuazzoniGiorgio Guazzoni , Luigi BarbeiriLuigi Barbeiri , Luigi Ferini-StrambiLuigi Ferini-Strambi , Sandro IannacconeSandro Iannaccone , Giliola CaloriGiliola Calori , Luciano NavaLuciano Nava , Patrizio RigattiPatrizio Rigatti , Giuliano PizziniGiuliano Pizzini , and Alberto MianiAlberto Miani View All Author Informationhttps://doi.org/10.1016/S0022-5347(01)64029-1AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: We assessed whether re-dosing of a vasoactive agent or the combination of a vasoactive injection and genital plus audiovisual sexual stimulation caused the greatest erectile effect to determine which of the 2 procedures would be better for dynamic penile color Doppler sonography in patients with erectile dysfunction. Materials and Methods: A total of 20 consecutive patients with erectile dysfunction underwent 2 sessions under real-time RigiScan* Dacomed Corp., Minneapolis, Minnesota. recording of penile erection. Session 1 consisted of adaptation in 10 minutes, intracavernous injection of 10 micro g. alprostadil in 10 minutes and re-dosing of 10 micro g. alprostadil in 10 minutes. Session 2 consisted of adaptation in 10 minutes, injection of 10 micro g. alprostadil in 10 minutes and genital plus audiovisual sexual stimulation in 10 minutes. The total duration of each session was 30 minutes. The order of the 2 sessions was randomly assigned with a week interval between each session. Results: Re-dosing and genital plus audiovisual sexual stimulation caused a significant increase in erectile response compared to the result seen after the first (re-dosing p <0.05, injection plus stimulation p <0.01). However, erectile response after the genital stimulation session was significantly greater than that after re-dosing (p <0.01). An erection comparable to the greatest spontaneous erection reported by the patient was much more frequently achieved after genital stimulation than after the re-dosing session (p <0.01). Conclusions: The combination of injection and stimulation caused a significantly greater erectile response than re-dosing. We suggest that the former always be used during color Doppler sonography to optimize the accuracy of the test. Re-dosing is suggested when an incomplete erectile response occurs after the injection plus stimulation phase. References 1 : Penile ultrasound.. Sem. Urol.1994; 12: 320. Google Scholar 2 : Relation of intracorporal pressure and end-diastolic velocity during duplex Doppler sonography in the evaluation of veno-occlusive dysfunction.. Int. J. Impotence Res.1994; 6: 125. Google Scholar 3 : Improved minimally-invasive assessment of penile hemodynamics: the combination of color Doppler sonography and injection-stimulation test.. Int. J. Impotence Res.1995; 7: 33. Google Scholar 4 : Mechanisms of venous leakage: a prospective clinicopathological correlation of corporeal function and structure.. J. Urol.1996; 156: 1320. Abstract, Google Scholar 5 : The effect of intracorporeal injection plus genital and audiovisual sexual stimulation versus second injection on penile color Doppler sonography parameters.. J. Urol.1996; 155: 536. Link, Google Scholar 6 : In vivo assessment of trabecular smooth muscle tone, its application in pharmacocavernosometry and analysis of intracavernous pressure determinants.. J. Urol.1995; 153: 1126. Abstract, Google Scholar 7 : The combined intracavernous injection and stimulation test: diagnostic accuracy.. J. Urol.1992; 148: 61. Abstract, Google Scholar From the Institute of Human Anatomy, Departments of Neurology and Urology, Unit of Medical Epidemiology, University of Milan School of Medicine and Scientific Institute H. San Raffaele, Milan, ItalyAccepted for publication July 25, 1997© 1998 by American Urological Association, Inc.FiguresReferencesRelatedDetailsCited byCOLOMBO R, BERTINI R, SALONIA A, NASPRO R, GHEZZI M, MAZZOCCOLI B, DEHO' F, MONTORSI F and RIGATTI P (2018) Overall Clinical Outcomes After Nerve and Seminal Sparing Radical Cystectomy for the Treatment of Organ Confined Bladder CancerJournal of Urology, VOL. 171, NO. 5, (1819-1822), Online publication date: 1-May-2004. Volume 159Issue 1January 1998Page: 113-115 Advertisement Copyright & Permissions© 1998 by American Urological Association, Inc.MetricsAuthor Information Francesco Montorsi More articles by this author Giorgio Guazzoni More articles by this author Luigi Barbeiri More articles by this author Luigi Ferini-Strambi More articles by this author Sandro Iannaccone More articles by this author Giliola Calori More articles by this author Luciano Nava More articles by this author Patrizio Rigatti More articles by this author Giuliano Pizzini More articles by this author Alberto Miani More articles by this author Expand All Advertisement PDF downloadLoading ...