Artigo Revisado por pares

UCLA Geriatric Grand Rounds: Diabetes in the Elderly

1987; Wiley; Volume: 35; Issue: 5 Linguagem: Inglês

10.1111/j.1532-5415.1987.tb04666.x

ISSN

1532-5415

Autores

Mark J. Rosenthal, Joan M. Hartnell, John E. Morley, Arshag D. Mooradian, M. A. Fiatarone, Fran E. Kaiser, Dan Osterweil,

Tópico(s)

Nutritional Studies and Diet

Resumo

Journal of the American Geriatrics SocietyVolume 35, Issue 5 p. 435-447 UCLA Geriatric Grand Rounds: Diabetes in the Elderly Mark J. Rosenthal MD, Mark J. Rosenthal MD Geriatric Research, Education, and Clinical Center Sepulveda VA Medical Center, Sepulveda, California Jewish Homes for the Aging, Reseda, California Multicampus Division of Geriatric Medicine, Department of Medicine, University of California, Los Angeles, California.Search for more papers by this authorJoan M. Hartnell MD, Joan M. Hartnell MD Geriatric Research, Education, and Clinical Center Sepulveda VA Medical Center, Sepulveda, California Jewish Homes for the Aging, Reseda, California Multicampus Division of Geriatric Medicine, Department of Medicine, University of California, Los Angeles, California.Search for more papers by this authorDr. John E. Morley MD, Corresponding Author Dr. John E. Morley MD Geriatric Research, Education, and Clinical Center Sepulveda VA Medical Center, Sepulveda, California Jewish Homes for the Aging, Reseda, California Multicampus Division of Geriatric Medicine, Department of Medicine, University of California, Los Angeles, California.Director, GRECC, VA Medical Center, 16111 Plummer Street, Sepulveda, CA.Search for more papers by this authorArshag D. Mooradian MD, Arshag D. Mooradian MD Geriatric Research, Education, and Clinical Center Sepulveda VA Medical Center, Sepulveda, California Jewish Homes for the Aging, Reseda, California Multicampus Division of Geriatric Medicine, Department of Medicine, University of California, Los Angeles, California.Search for more papers by this authorMaria Fiatarone MD, Maria Fiatarone MD Geriatric Research, Education, and Clinical Center Sepulveda VA Medical Center, Sepulveda, California Jewish Homes for the Aging, Reseda, California Multicampus Division of Geriatric Medicine, Department of Medicine, University of California, Los Angeles, California.Search for more papers by this authorFran E. Kaiser MD, Fran E. Kaiser MD Geriatric Research, Education, and Clinical Center Sepulveda VA Medical Center, Sepulveda, California Jewish Homes for the Aging, Reseda, California Multicampus Division of Geriatric Medicine, Department of Medicine, University of California, Los Angeles, California.Search for more papers by this authorDan Osterweil MD, Dan Osterweil MD Geriatric Research, Education, and Clinical Center Sepulveda VA Medical Center, Sepulveda, California Jewish Homes for the Aging, Reseda, California Multicampus Division of Geriatric Medicine, Department of Medicine, University of California, Los Angeles, California.Search for more papers by this author Mark J. Rosenthal MD, Mark J. Rosenthal MD Geriatric Research, Education, and Clinical Center Sepulveda VA Medical Center, Sepulveda, California Jewish Homes for the Aging, Reseda, California Multicampus Division of Geriatric Medicine, Department of Medicine, University of California, Los Angeles, California.Search for more papers by this authorJoan M. Hartnell MD, Joan M. Hartnell MD Geriatric Research, Education, and Clinical Center Sepulveda VA Medical Center, Sepulveda, California Jewish Homes for the Aging, Reseda, California Multicampus Division of Geriatric Medicine, Department of Medicine, University of California, Los Angeles, California.Search for more papers by this authorDr. John E. Morley MD, Corresponding Author Dr. John E. Morley MD Geriatric Research, Education, and Clinical Center Sepulveda VA Medical Center, Sepulveda, California Jewish Homes for the Aging, Reseda, California Multicampus Division of Geriatric Medicine, Department of Medicine, University of California, Los Angeles, California.Director, GRECC, VA Medical Center, 16111 Plummer Street, Sepulveda, CA.Search for more papers by this authorArshag D. Mooradian MD, Arshag D. Mooradian MD Geriatric Research, Education, and Clinical Center Sepulveda VA Medical Center, Sepulveda, California Jewish Homes for the Aging, Reseda, California Multicampus Division of Geriatric Medicine, Department of Medicine, University of California, Los Angeles, California.Search for more papers by this authorMaria Fiatarone MD, Maria Fiatarone MD Geriatric Research, Education, and Clinical Center Sepulveda VA Medical Center, Sepulveda, California Jewish Homes for the Aging, Reseda, California Multicampus Division of Geriatric Medicine, Department of Medicine, University of California, Los Angeles, California.Search for more papers by this authorFran E. Kaiser MD, Fran E. Kaiser MD Geriatric Research, Education, and Clinical Center Sepulveda VA Medical Center, Sepulveda, California Jewish Homes for the Aging, Reseda, California Multicampus Division of Geriatric Medicine, Department of Medicine, University of California, Los Angeles, California.Search for more papers by this authorDan Osterweil MD, Dan Osterweil MD Geriatric Research, Education, and Clinical Center Sepulveda VA Medical Center, Sepulveda, California Jewish Homes for the Aging, Reseda, California Multicampus Division of Geriatric Medicine, Department of Medicine, University of California, Los Angeles, California.Search for more papers by this author First published: May 1987 https://doi.org/10.1111/j.1532-5415.1987.tb04666.xCitations: 10 Dr. Kaiser is a Hartford Geriatric Faculty Development Award Recipient. Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat REFERENCES 1 Bennett PH: Diabetes in the elderly: Diagnosis and epidemiology. Geriatrics 39: 37–41, 1984. 2 Reaven GM, Reaven EP: Age, glucose intolerance, and noninsulin-dependent diabetes mellitus. J Am Geriatr Soc 33: 286–290, 1985. 3 Chen M., Bergman RN, Pacini G., et al: Pathogenesis of age-related glucose intolerance in man: Insulin resistance and decreased B-cell function. J Clin Endocrinol Metab 60: 13–20, 1985. 4 White NH, Skor DA, Cryer PE, et al: Identification of Type I diabetic patients at increased risk for hypoglycemia during intensive therapy. N Engl J Med 308: 485–491, 1983. 5 Yoo J., Peter S., Kleinfeld M.: Transient hypoglycemic hemiparesis in an elderly patient. J Am Geriatr Soc 34: 479–481, 1986. 6 Asplund K., Wilholm BE, Lithner F.: Glibenclamide-associated hypoglycemia: A report on 57 cases. Dia-betologia 24: 412–417, 1983. 7 Shibasaki T., Shizume K., Nakahara M., et al: Age-related changes in plasma growth hormone response to growth hormone releasing factor in man. J Clin Endocrinol Metab 58: 212–214, 1984. 8 Blichert-Tuft M.: Secretion of corticotrophin and somatotrophin by the senescent adenohypophysis in man. Acta Endocrinol (Suppl) p 195, 1975. 9 Kalk WJ, Vanik AI, Pimstone BL, et al: Growth hormone reponse to insulin hypoglycemia in the elderly. J Gerontol 28: 431–433, 1973. 10 Muggeo M., Fedele D., Tiengo A., et al: Human GH and Cortisol response to insulin stimulation in the aged. J Gerontol 30: 546–551, 1975. 11 Meneilly GS, Minaker KL, Young JB, et al: Counter-regulatory responses to insulin-induced glucose re-duction in the elderly. J Clin Endocrinol Metab 61: 178–182, 1985. 12 Bolli GB, Genich JE: The “Dawn” phenomenon—A common occurrence in both noninsulin-dependent diabetes mellitus. N Engl J Med 310: 746–750, 1984. 13 Rosenthal MJ, Argoud GM: Absence of the dawn phenomenon in healthy elderly male subjects. Diabetes 35: 16A, 1986. 14 Meneilly GS, Elahi D., Minaker KL, et al: The dawn phenomenon does not occur in normal elderly subjects. J Clin Endocrinol Metab 63: 292–296, 1986. 15 Carroll P., Matz R.: Uncontrolled diabetes mellitus in adults: Experience in treatment of diabetic ketoacidosis and hyperosmolar nonketotic coma with low-dose insulin and uniform treatment regimen. Diabetes Care 6: 579–585, 1983. 16 Phillips PA, Rolls RJ, Ledingham JGG, et al: Reduced thirst after water deprivation in healthy elderly men. N Engl J Med 311: 753–759, 1984. 17 Nathan DM, Singer DE, Godine JE, et al: Retinopathy in older Type II diabetics: Association with glucose control. Diabetes 35: 797–801, 1986. 18 Bresnick GH, Groo A., Palta M., et al: Urinary glucose testing inaccuracies among diabetic patients: Effect of acquired color vision deficiency caused by diabetic retinopathy. Arch Ophthalmol 102: 1489–1496, 1984. 19 Morley GK, Mooradian AD, Levine AS, et al: Why is diabetic neuropathy painful? The effect of glucose on pain perception in humans. Am J Med 77: 79–83, 1984. 20 Simon GS, Dewey WL: Narcotics and diabetes. I. The effects of streptozotocin-induced diabetes on the antinociceptive potency of morphine. J Pharmacol Exp Ther 218: 318–323, 1981. 21 Morley JE, Levine AS, Yim GK, et al: Opioid modulation of appetite. Neurosci Biobehav Rev 7: 281–305, 1983. 22 Pirart J.: Diabetes mellitus and its degenerative complications: A prospective study of 4,400 patients observed between 1948 and 1973. Diabetes Care 1: 168–188, 1978. 23 Perlmuter LC, Hakami MK, Hodgson-Harrington C., et al: Decreased cognitive function in aging, noninsulin -dependent diabetic patients. Am J Med 77: 1043–1048, 1984. 24 Morley JE: Impotence. Am J Med 80: 897–905, 1986. 25 Schambelan M., Sebastian A.: Hyporeninemic hypoaldosteronism. Adv Intern Med 24: 385–405, 1979. 26 Neil HAW, Dawson JA, Baker JE: Risk of hypothermia in elderly patients with diabetes. Br Med J 293: 416–418, 1986. 27 Trence DL, Morley JE, Handwerger BS: Polyglandular autoimmune syndromes. Am J Med 77: 107–116, 1984. 28 Morley JE: Nutritional status of the elderly. Am J Med 81: 679–695, 1986. 29 Master AM, Lasser RP: Tables of average weight and height of Americans aged 65 to 94 years. J Am Med Assoc 172: 658–662, 1960. 30 Gersovitz M., Motil K., Munro HN, et al: Human protein requirements: Assessment of the adequacy of the current Recommended Dietary Allowance for dietary protein in elderly men and women. Am J Clin Nutr 35: 6–14, 1982. 31 Nuttall FQ, Mooradian AD, Gannon MC, et al: Effect of protein ingestion on the glucose and insulin response to a standardized oral glucose load. Diabetes Care 7: 465–470, 1984. 32 Nuttall FQ: Diet and the diabetic patient. Diabetes Care 6: 197–207, 1983. 33 Jenkins DJA, Wolever TMS, Taylor RH, et al: Glycemic index of foods: A physiological basis for carbohydrate exchange. Am J Clin Nutr 34: 362–366, 1981. 34 Nuttall FQ, Mooradian AD, DeMarais R., et al: The glycemic effect of different meals approximately iso-caloric and similar in protein, carbohydrate, and fat content as calculated using the ASA exchange lists. Diabetes Care 6: 432–435, 1983. 35 Mooradian AD, Morley JE: Micronutrient status in diabetes mellitus. Am J Clin Nutr 45: 877–895, 1987. 36 Thomson CD, Rea H., Robinson MF, et al: Low blood selenium concentrations and glutathione peroxidase activities in elderly people. Proc Univ Otago Med Sch 55: 18–26, 1977. 37 Vranic M., Berger M.: Review and Abstracts. Exercise and diabetes mellitus. Diabetes 28: 147–167, 1979. 38 Hollenbeck CB, Haskell W., Rosenthal M., et al: Effect of habitual physical activity on regulation of insulin-stimulated glucose disposal in older males. J Am Geriatr Soc 33: 273–277, 1984. 39 Seals DR, Hagberg JM, Allen WK, et al: Glucose tolerance in young and older athletes and sedentary men. J Appl Physiol 56(6): 1521–1525, 1984. 40 Zavaroni I., Dall'Aglio E., Bruschi F., et al: Effect of age and environmental factors on glucose tolerance and insulin secretion in a worker population. J Am Geriatr Soc 34: 271–275, 1986. 41 Seals DR, Hagberg JM, Hurley BF, et al: Effects of endurance training on glucose tolerance and plasma lipid levels in older men and women. JAMA 252: 645–649, 1984. 42 Saltin B., Lindgarde F., Houston M., et al: Physical training and glucose tolerance in middle-aged men with chemical diabetes. Diabetes 28(Suppl 1): 30–32, 1979. 43 Ruderman NB, Ganda OP, Johansen K.: The effect of physical training on glucose tolerance and plasma lipids in maturity-onset diabetes. Diabetes 28(Suppl 1): 89–92, 1979. 44 Schneider SH, Ruderman NR, Amorora LF, et al: Physical training in noninsulin-dependent diabetics. Diabetes 30(Suppl 1): 74A, 1981. 45 Lindgarde F., Malmquist J., Balke B.: Physical fitness, insulin secretion, and glucose tolerance in healthy males and mild Type II diabetes. Acta Diabet Lat 20: 33–40, 1983. 46 Cuppers HJ, Romanowski S., Liesen H., et al: Metabolic effects of endurance- and strength-exercise training programes in normal weight Type II (noninsulin-dependent) diabetes mellitus. Diabetes 33: 266A, 1984. 47 Bogardus C., Ravussin E., Robbins DC, et al: Effects of physical training and diet therapy on carbohydrate metabolism in patients with glucose intolerance and noninsulin-dependent diabetes mellitus. Diabetes 33: 311–318, 1984. 48 Schneider SH, Amorosa LF, Khachadurian AK, et al: Studies on the mechanism of improved glucose control during regular exercise in Type 2 (noninsulin-dependent) diabetes. Diabetologia 26: 355–360, 1984. 49 Reitman JS, Vasquez B., Klimes I., et al: Improvements of glucose homeostasis after exercise training in noninsulin-dependent diabetes. Diabetes Care 7(5): 434–441, 1984. 50 Trovati M., Carta Q., Cavalot F., et al: Influence of physical training on blood glucose control, glucose tolerance, insulin secretion, and insulin action in noninsulin-dependent diabetic patients. Diabetes Care 7(5): 416–420, 1984. 51 Krotkiewski M., Lonnroth P., Mandroukas K., et al: The effects of physical training on glucose metabolism in obesity and Type 2 (noninsulin-dependent) diabetes mellitus. Diabetologia 28: 881–890, 1985. 52 Goldberg L., Elliot DL: Symposium on Medical Aspects of Exercise. Medical Clinics of North America 69(1): 3–214, 1985. 53 Lipson LG: Diabetes in the elderly: Diagnosis, pathogenesis, and therapy. Am J Med 80(Suppl 5A): 10–21, 1986. 54 Weissman PN, Shenkman L., Gregerman RI: Chlorpropamide hyponatremia—Drug-induced inappropriate antidiuretic hormone activity. N Engl J Med 284: 65–71, 1971. 55 Kadowaki T., Hagura R., Kajinuma H., et al: Chlropropamide-induced hyponatremia: Incidence and risk factors. Diabetes Care 6: 468–471, 1983. 56 Seltzer HS: Drug-induced hypoglycemia: A review based on 473 cases. Diabetes 21: 955–966, 1972. 57 Rowe JW, Andres R., Tobin JD, et al: The effect of age creatinine clearance in man. A cross-sectional and longitudinal study. J Gerontol 31: 144–163, 1976. 58 Shen SW, Bressler R.: Clinical pharmacology of the oral antidiabetic agents. N Engl J Med 296: 493–497, 1977. 59 Jackson JE, Bressler R.: Clinical pharmacology of sulfonylurea hypoglycemia agents. Drugs 22: 211–245; 295–320, 1981. 60 Clark BF, Campbell IW: Long-term comparative trial of glibenclamide and chlorpropamide in diet failed, maturity onset diabetics. Lancet i: 246, 1975. 61 Asplund K., Wiholm BE, Lithner F.: Glibenclamide associated hypoglycemia: A report on 57 cases. Diabetologia 24: 412–417, 1983. 62 Feldman JM: Review of glyburide after one year on the market. Am J Med 79(Suppl 3B): 102–108, 1985. 63 Balant L., Zahnd G., Gorgia A., et al: Pharmacokinetics of glipizide in man: Influence of renal insufficiency. Diabetologia 9(Suppl): 331–338, 1973. 64 Schmidt HAE, Schoog M., Schweer KH, et al: Pharmacokinetics and pharmacodynamics as well as metabolism following orally and intravenously administered 14C glipizide, a new anti-diabetic. Diabetologia 9(Suppl): 320–330, 1973. 65 Tamassia V.: Pharmacokinetics and bioavailability of glipizide. Curr Med Res Opin 3(Suppl 1): 20–30, 1975. 66 Lebovitz HE: Glipizide: A second generation sulfonylurea hypoglycemic agent. Pharmacotherapy 5: 63–77, 1985. 67 Ginier P., Madan S., Farjardo F.: Once daily use of glyburide. Am J Med 79(Suppl 3B): 72–77, 1985. 68 Groop L., Harno K.: Diurnal pattern of plasma insulin and blood glucose during glibenclamide and glipizide therapy in elderly diabetics. Acta Endocrinol (Suppl) 239: 44–52, 1986. 69 Kerson CM, Baile GR: Do diabetic patients inject accurate doses of insulin? Diabetes Care 4: 333, 1981. 70 Puxty JAM, Hunter DM, Burr WA: Accuracy of insulin injection in elderly patients. Br Med J 287: 1762, 1983. 71 National Center for Health Statistics Chronic Conditions and Impairments of Nursing Home Residents: United States 1968 Vital and Health Statistics, Series 12, No. 22 IDHEW Pub. No. HRA, Rockville, Maryland, US Department HEW, 1973. 72 Osterweil D., Mooradian AD, Petrasek D., et al: Diabetes mellitus in ambulatory elderly and nursing home patients: A survey of clinical characteristics and management. Clin Res 35: 98A, 1987. 73 Report of the National Commission on Diabetes to Congress of the United States, Vol. 3, Part 1, U.S. Department HEW, 1976, p 68. 74 Grobin W.: Diabetes in the aged: Underdiagnosis and overtreatment. Can Med Assn J 103: 915–923, 1970. 75 Wheat LJ: Infection and diabetes mellitus. Diabetes Care 3: 187–197, 1980. 76 Pulsinell WA, Levy DE, Sigsbee B., et al: Increased damage after ischemic stroke in patients with or without established diabetes mellitus. Am J Med 74: 540–544, 1983. 77 Zimmer JG, Williams TF: Spectrum of severity and control of diabetes mellitus in skilled nursing facilities. J Am Geriatr Soc 26(10): 443–452, 1978. Citing Literature Volume35, Issue5May 1987Pages 435-447 ReferencesRelatedInformation

Referência(s)