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Stem cells: sources and applications

2002; Wiley; Volume: 27; Issue: 4 Linguagem: Inglês

10.1046/j.1365-2273.2002.00579.x

1365-2273

A. Vats, Neil Tolley, J. M. Polak, Lee Buttery,

Tissue Engineering and Regenerative Medicine

Tissue engineering is a multidisciplinary area of research aimed at regeneration of tissues and restoration of function of organs through implantation of cells/tissues grown outside the body, or stimulating cells to grow into implanted matrix. In this short review, some of the most recent developments in the use of stem cells for tissue repair and regeneration will be discussed. There is no doubt that stem cells derived from adult and embryonic sources hold great therapeutic potential but it is clear that there is still much research required before their use is commonplace. There is much debate over adult versus embryonic stem cells and whether both are required. It is probably too early to disregard one or other of these cell sources. With regard to embryonic stem cells, the major concern relates to the ethics of their creation and the proposed practice of therapeutic cloning.