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Forgetting of a drug-conditional discrimination

1979; Elsevier BV; Volume: 22; Issue: 5 Linguagem: Inglês

10.1016/0031-9384(79)90327-5

1873-507X

Norman E. Spear, Gregory J. Smith, Alan P. Sherr, Richard G. Bryan,

Neurotransmitter Receptor Influence on Behavior

Rats were trained on a drug-conditional discrimination to escape footshock in a T maze. Over a period of days rats learned to approach one goal box while under a pentobarbital drug state and another while under a saline drug state. Retention of this discrimination was then assessed with the rat under either a pentobarbital or saline state, after an interval of 24 hours, 7 days, 30 days or 60 days. The results indicated little forgetting overall, with better long-term retention of the drug discrimination when the rats were tested under the pentobarbital state than under the saline state.