Phospholipid composition of guinea pig lung lavage
1985; Wiley; Volume: 20; Issue: 1 Linguagem: Inglês
10.1007/bf02534355
ISSN1558-9307
AutoresArshad Q. Khan, Matthew O. Sikpi, Salil K. Das,
Tópico(s)Liver Disease Diagnosis and Treatment
ResumoAbstract Phospholipids from guinea pig lung lavage were analyzed. The total lavage phospholipid content was 2.65+0.67 mg, per gram of lung, which accounted for 85% of the total lipids in lung wash. Phosphatidylcholine (PC) accounted for over 60% of the total phospholipids. The other phospholipids factions, in order of pedominance, were phosphatidylinositol (PI), phosphatidylserine (PS), sphingomyelin (SPH), phosphatidylethanolamine (PE), phosphatidylglycerol (PG) and lysophosphatidyl‐choline (LPC). Disaturated phosphatidylcholine (DSPC) comprised 80% of the total PC, and it contained ostly palmitic acid. The DSPC content of the lung lavage fluid per square meter of alveolar surface area was 5.76±0.42 mg.
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