Neurogenic Benign Fasciculations, Pseudomyotonia, and Pseudotetany
1981; American Medical Association; Volume: 38; Issue: 5 Linguagem: Inglês
10.1001/archneur.1981.00510050048006
ISSN1538-3687
Autores Tópico(s)Autoimmune Neurological Disorders and Treatments
ResumoWe studied two patients with abnormal spontaneous muscular activity.The first had widespread fasciculations, painful spasms, delayed muscular relaxation, and hyperhidrosis.Improvement occurred after several years.The second case had generalized paresthesia, mild stiffness, a positive resull from Trousseau's test, and was relieved by adminis tration of c arbamazepine.Both patients had abnormal c onduc tion veloc ity.Exami nation of musc le biopsy spéc imens dis c losed fiber type grouping and in c reased c ollatéral ramifi c ation of motor axons.Thèse observations exemplify symptoms and signs that resemble those of myoto nia and tetany and oc c asionally oc c ur in partial denervation.They provide addi tional évidenc e of the neurogenic nature of Isaac sMertens syndrome.(Arch Neurol 1981;38:282287)\UQ studied two cases that illustrate ' ' the unusual features occasionally occurring in denervation.Their clas sification is unsett l ed, but they resemb l e a patho l ogica l condition characterized by persistent invol unta ry muscular activity that is often asso ciated with excessive sweating and sometimes with musc l e wasting and weakness.According to Wel ch et a l ,' this condition has been recognized for nearl y 100 years and reported under various names, inc l uding continuons musc l e fiber activity," ' neuromyoto
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