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Quinolizidine Alkaloids from Sophora alopecuroides

2000; American Chemical Society; Volume: 63; Issue: 2 Linguagem: Inglês

10.1021/np990351v

1520-6025

Atta‐ur Rahman, M. Iqbal Choudhary, Khalid Parvez, Aftab Ahmed, Farzana Akhtar, M. Nur‐e‐Alam, Naeem M. Hassan,

Natural product bioactivities and synthesis

A new matrine-type alkaloid, 7alpha-hydroxysophoramine (1), was isolated from the aerial parts of Sophora alopecuroides together with eight known alkaloids, 12beta-hydroxysophocarpine (2), sophoramine (3), 14beta-hydroxymatrine, matrine, sophoridine, sophocarpine, adenocarpine, and baptifoline. The structures of compounds 1-3 were confirmed through single-crystal X-ray diffraction analysis.