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Oral cancer in 57,518 industrial workers of Gujarat, India.A prevalence and followup study

1976; Wiley; Volume: 37; Issue: 4 Linguagem: Inglês

10.1002/1097-0142(197604)37

1097-0142

A. M. Malaowalla, Sol Silverman, N. J. Mani, K. F. Bilimoria, Lowell W. Smith,

Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

In Gujarat, India, 57,518 industrial workers over 35 years old were examined for oral lesions. At a two-year interval, 43,654 workers were re-examined. Biopsies were taken from 13,223 lesions. In the initial examination, 29 oral cancers were diagnosed, representing a prevalence rate of 50/100,000. After two years, 22 new oral cancers were diagnosed, representing an incidence rate of 25/100,000 per year. Over 90% were squamous carcinomas, with the majority of lesions occurring in the oropharynx and tongue. All patients who developed squamous carcinomas had tobacco habits, while 85% of the entire study population had oral habits in some form. Their most common habits were smoking tobacco alone or in combination with chewing "pan"/"supari." Of the carcinomas that developed during a two-year interval, 62% appeared in previously normal appearing mucosa. Leukoplakia was the only oral lesion that proved to be precancerous, with a transformation rate of 0.13% in a two-year interval.