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ABC transporter-mediated uptake of iron, siderophores, heme and vitamin B12

2001; Elsevier BV; Volume: 152; Issue: 3-4 Linguagem: Inglês

10.1016/s0923-2508(01)01200-1

1769-7123

Wolfgang Köster,

Porphyrin Metabolism and Disorders

Microbes have developed a number of different strategies to utilize iron, which is a vital element for most organisms but not always readily available from the environment. Based on experimental studies and sequence analysis data, this article gives a short overview of ABC transporters related to iron uptake: components of three distinct families mediate the translocation of iron, siderophores, heme and vitamin B12 across the cytoplasmic membrane of bacteria.