PDMS-based microfluidic devices for biomedical applications
2002; Elsevier BV; Volume: 61-62; Linguagem: Inglês
10.1016/s0167-9317(02)00494-x
ISSN1873-5568
Autores Tópico(s)Electrowetting and Microfluidic Technologies
ResumoMicrofluidic devices provide a number of advantageous features for microscale biochemical systems for analysis and/or synthesis. A PDMS (polydimethylsiloxane) microchip, for instance, which has microchannels for electrophoretic separation can be easily fabricated through a molding process. Sealing of those channels does not need any elaborate bonding processes which are usually required for glass chips. We have been working on PDMS-based microfluidic devices for biomedical applications, where microreactors, microchips for capillary gel electrophoresis, and hydrophobic vent valves are successfully fabricated and operated. Fundamentals of PDMS-based microfluidic devices and their functions are described as well as the experimental results.
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