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BIBTEX RIS

The stereostructure of candicidin D

2015; Springer Nature; Volume: 68; Issue: 8 Linguagem: Inglês

10.1038/ja.2015.17

ISSN

1881-1469

Autores

Katarzyna Szwarc, Paweł Szczeblewski, Paweł Sowiński, E. Borowski, Jan Pawlak,

Tópico(s)

Phytochemistry and Biological Activities

Resumo

The candicidin D stereostructure was established based on NMR studies including DQF-COSY, ROESY, HSQC and HMBC experiments. The relative configurations of the candicidin D stereogenic centers were assigned as the following: 9R*, 11S*, 13S*, 15R*, 17S*, 18R*, 19S*, 21R*, 36S*, 37R*, 38S*, 40S* and 41S*. The geometry of the heptaene chromophore was defined as 22E, 24E, 26Z, 28Z, 30E, 32E and 34E.

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