Association Between Metformin Therapy and Mortality After Breast Cancer
2013; American Diabetes Association; Volume: 36; Issue: 10 Linguagem: Inglês
10.2337/dc12-2535
ISSN1935-5548
AutoresIliana C. Lega, Peter C. Austin, Andrea Gruneir, Pamela J. Goodwin, Paula A. Rochon, Lorraine L. Lipscombe,
Tópico(s)Cancer-related Molecular Pathways
ResumoMetformin has been associated with a reduction in breast cancer risk and may improve survival after cancer through direct and indirect tumor-suppressing mechanisms. The purpose of this study was to evaluate the effect of metformin therapy on survival in women with breast cancer using methods that accounted for the duration of treatment with glucose-lowering therapies.
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