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Synthesis of 7,5-fused bicyclic lactams by stereoselective radical cyclization

1994; Elsevier BV; Volume: 35; Issue: 23 Linguagem: Inglês

10.1016/s0040-4039(00)76732-3

1873-3581

Lino Colombo, Marcello Di Giacomo, Gianluca Papeo, Oliviero Carugo, Carlo Scolastico, Leonardo Manzoni,

Chemical Synthesis and Analysis

7,5-Fused bicyclic lactams of type 1 were synthesised by a route involving the radical cyclization of the intermediate 2. High level of stereoselection was obtained in this reaction.