Structural characterization of an immunoenhancing heteroglycan isolated from an aqueous extract of an edible mushroom, Lentinus squarrosulus (Mont.) Singer
2010; Elsevier BV; Volume: 345; Issue: 17 Linguagem: Inglês
10.1016/j.carres.2010.09.015
ISSN1873-426X
AutoresSanjoy K. Bhunia, Biswajit Dey, Kankan K. Maity, Sukesh Patra, Soumitra Mandal, Swatilekha Maiti, T. K. Maiti, Samir Ranjan Sikdar, Syed S. Islam,
Tópico(s)Seaweed-derived Bioactive Compounds
ResumoA water-soluble polysaccharide, isolated from the hot water extract of the fruiting bodies of an edible mushroom, Lentinus squarrosulus (Mont.) Singer was found to contain d-galactose, l-fucose, and d-glucose in a molar ratio of nearly 1:1:5. Structural investigation of the polysaccharide was carried out using acid hydrolysis, methylation analysis, periodate oxidation study, and NMR experiments ((1)H, (13)C, DQF-COSY, TOCSY, NOESY, ROESY, HMQC, and HMBC). On the basis of above-mentioned experiments, the structure of the repeating unit of the polysaccharide was established as: This polysaccharide showed macrophage as well as splenocyte and thymocyte activation.
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