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Red cell phospholipids in schizophrenia

1982; Elsevier BV; Volume: 31; Issue: 26 Linguagem: Inglês

10.1016/0024-3205(82)90074-1

1879-0631

Andrew Lautin, Donna Mandio Cordasco, David J. Segarnick, Laurence M. Wood, M.F. Mason, Adam Wolkin, John Rotrosen,

Diabetes and associated disorders

Phospholipids in red blood cells (RBCs) of schizophrenics and controls were determined. Three different RBC preparations and two different extraction methods were used. Phospholipids were separated by thin layer chromatography and by high pressure liquid chromatography, and were quantified by phosphorus analysis and by ultraviolet absorption. Findings were consistent with values previously reported for normals. However, in contrast to recent reports of elevated phosphatidylserine levels in schizophrenics' RBCs, we observed no differences between populations.