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BIBTEX RIS

Vertical transmission of HIV in Rio de Janeiro, Brazil

2003; Lippincott Williams & Wilkins; Volume: 17; Issue: 12 Linguagem: Inglês

10.1097/00002030-200308150-00016

1473-5571

Esaú João, Daisy Maria Machado, Jacqueline A. Menezes, Haroldo José de Matos, Guilherme Amaral Calvet, Marcos Machado d'Ippolito, Luísa T Salgado, Sonia S Silva, G. Bazin, Ricardo Cerqueira Campos Braga,

Adolescent Sexual and Reproductive Health

A cohort of 297 HIV-infected pregnant women was followed from January 1996 to December 2001. The overall transmission rate was 3.57% and remained constant over time. Low birth-weight was independently associated with a higher risk of vertical transmission (P=0.0072), whereas a longer duration of antiretroviral drugs during pregnancy was independently associated with a lower risk of transmission (P=0.0084). Further decreases in transmission should be obtained by initiating prophylaxis earlier in pregnancy.