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Solid Phase Synthesis of DNA Under a Non-Depurinating Condition with a Base Labile 5′-Protecting Group (Fmoc) Using Phosphiteamidite Approach

1987; Taylor & Francis; Volume: 6; Issue: 1-2 Linguagem: Inglês

10.1080/07328318708056256

2332-3892

N. Balgobin, Jyoti Chattopadhyaya,

Advanced biosensing and bioanalysis techniques

Abstract 5′-Fmoc protected 2′ -deoxynucleoside building blocks have been employed in DNA synthesis in order to remedy the depurination problem.