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Genetic make up and structure of Colombian populations by means of uniparental and biparental DNA markers

2010; Wiley; Volume: 143; Issue: 1 Linguagem: Inglês

10.1002/ajpa.21270

1096-8644

Winston Rojas, María Victoria Parra, Omer Campo, María Antonieta, Juan G. Lopera, William Arias, Constanza Duque, Andrés Naranjo, Jharley Jair García, Candelaria Vergara, Jaime Lopera-Madrid, Eric H. Hernandez, Ana Valencia, Y Caicedo, Jorge Mauricio Cuartas Arias, Javier Gutiérrez, Sergio López, Andrés Ruiz‐Linares, Gabriel Bedoya,

Race, Genetics, and Society

Abstract Colombia is a country with great geographic heterogeneity and marked regional differences in pre‐Columbian native population density and in the extent of past African and European immigration. As a result, Colombia has one of the most diverse populations in Latin America. Here we evaluated ancestry in over 1,700 individuals from 24 Colombian populations using biparental (autosomal and X‐Chromosome), maternal (mtDNA), and paternal (Y‐chromosome) markers. Autosomal ancestry varies markedly both within and between regions, confirming the great genetic diversity of the Colombian population. The X‐chromosome, mtDNA, and Y‐chromosome data indicate that there is a pattern across regions indicative of admixture involving predominantly Native American women and European and African men. Am J Phys Anthropol 143:13–20, 2010. © 2010 Wiley‐Liss, Inc.