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Ventilatory response of llama to hypoxia at sea level and high altitude

1968; Elsevier BV; Volume: 5; Issue: 2 Linguagem: Inglês

10.1016/0034-5687(68)90065-0

1872-7611

J.G. Brooks, S.M. Tenney,

Thermal Regulation in Medicine

Ventilatory response to hypoxia was studied at sea level in two second generation sea level llamas and at high altitude in two native llamas, born and reared at 3790 m. The purpose was to discover whether high altitude llamas, like man, lose their hypoxic response after long term high altitude residence. Paco2 during all studies of hypoxic ventilatory response was controlled at the highest value which has no discernible effect on ventilation when PiO2=150 mm Hg (the inflexion point of a “dog leg” CO2 response curve). Threshold and sensitivity values of the hypoxic responses of the sea level llamas and the native highland llamas were not significantly different and fell within the normal range reported for sea level man, when steady state measurements are made. The llama, apparently in contrast to man, does not lose its ventilatory response to hypoxia as a result of long time exposure to ambient hypoxia.