Retrospective Evaluation of Intussusception in Under-Five Children in Nigeria
2014; Scientific Research Publishing; Volume: 04; Issue: 03 Linguagem: Inglês
10.4236/wjv.2014.43015
ISSN2160-5823
AutoresBeckie N. Tagbo, Jason M. Mwenda, Christopher Bismarck Eke, Tagbo Oguonu, Sebastin Ekemze, Uchechukwu Obiora Ezomike, Benedict Onyeka Edelu, Ogechukwu F Amadi, Ifeyinwa Okeke, Okechukwu Ani, Roservelt Okechukwu Nnani, Vina Okafor, Henrietta Uche Okafor, Egbuna Obidike, Emmanuel Abanida, Christopher Ononiwu Elemuwa, Toyin Odetunde,
Tópico(s)Gastrointestinal disorders and treatments
ResumoBackground: Assessment of the safety profile of the new rotavirus vaccines in Africa requires base-line epidemiological data on intussusception. Hence, this study was aimed at describing the prevalence and associated factors of intussusception in under-five children in Enugu, Southeast, Nigeria. Methods: This was a retrospective descriptive study involving the sixty reported cases of intussusception in under-five children admitted in a hospital in Enugu between 2007 and 2012. Cases of intussusception were selected using the Brighton collaboration intussusception working group level I diagnostic criteria. Information sought from the patients’ folders included demographic characteristics and clinical manifestations including history of previous rotavirus vaccination, duration of illness prior to presentation, diarrhoea, vomiting, passage of red currant jelly-like stool, abdominal mass and distension, method of diagnosis, treatment option(s) employed and their outcomes. The data was analyzed using SPSS version 17.0. Results: The majority of the cases were aged less than one year (53; 88.3%) while the average incidence of intussusception was 0.1 per 1000. None of the cases had received rotavirus vaccinations. The common clinical presentations were vomiting, 55 (17.2%), passage of red currant stool 50 (15.6%), fever 50 (15.6%) and abnormal/absent bowel sound 43 (15.9%). Diagnosis was essentially with the aid of abdominal ultrasonography, 38 (63.3%) while surgery (laparotomy) was the treatment of choice in most cases 48 (80.0%). The case fatality rate was 3 (5.0%). Conclusion: None of the cases studied could be directly linked to rotavirus vaccinations. But seasonal peak incidence coincided with rotavirus diarrhea peak incidence. Efforts should be made to institute post-rotavirus vaccine licensure prospective surveillance study in order to fully determine any relationship between rotavirus vaccination and intussusception in Enugu, South east, Nigeria.
Referência(s)