Artigo Revisado por pares

On the effect of melatonin upon human brain. Its possible therapeutic implications

1971; Elsevier BV; Volume: 10; Issue: 15 Linguagem: Inglês

10.1016/0024-3205(71)90155-x

ISSN

1879-0631

Autores

Fernando Antón‐Tay, José-Luis Dı́az, Augusto Fernández‐Guardiola,

Tópico(s)

Sleep and Wakefulness Research

Resumo

Various doses of melatonin were administered to normal and epileptic subjects. Increase of EEG alpha activity, sleep, imagery, and a feeling of well-being and elation were found. A decrease in paroxistic grapho-elements of the epileptic patients was also noticed. When two parkinsonians received 1.2 g of melatonin orally for four weeks, a striking improvement in the symptoms and signs of the disease was detected.

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