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BIBTEX RIS

In Vitro Pharmacodynamic Characteristics of Nystatin Including Time-Kill and Postantifungal Effect

2000; American Society for Microbiology; Volume: 44; Issue: 10 Linguagem: Inglês

10.1128/aac.44.10.2887-2890.2000

ISSN

1098-6596

Autores

Shana M. Gunderson, Holly Hoffman, Erika J. Ernst, Michael A. Pfaller, Michael E. Klepser,

Tópico(s)

Fungal Infections and Studies

Resumo

ABSTRACT Four Candida albicans isolates and six non- albicans Candida isolates were evaluated by time-kill methods to characterize the relationship between nystatin concentrations, the rate and extent of fungicidal activity, and the postantifungal effect (PAFE). Against Candida species, nystatin exhibits concentration-dependent fungicidal activity and a pronounced PAFE.

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