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IL-17 and GM-CSF Expression Are Antagonistically Regulated by Human T Helper Cells

2014; American Association for the Advancement of Science; Volume: 6; Issue: 241 Linguagem: Inglês

10.1126/scitranslmed.3008706

1946-6242

Rebecca Noster, René Riedel, Mir‐Farzin Mashreghi, Helena Radbruch, Lutz Harms, Claudia Haftmann, Hyun‐Dong Chang, Andreas Radbruch, Christina E. Zielinski,

Immunotherapy and Immune Responses

GM-CSF–producing T helper cells in humans follow a distinct regulation program as compared to T H 17 cells and are associated with multiple sclerosis.