Artigo Revisado por pares

Determination of proteins by fluorescence quenching of erythrosin B

1996; Elsevier BV; Volume: 333; Issue: 1-2 Linguagem: Inglês

10.1016/0003-2670(96)00280-2

ISSN

1873-4324

Autores

Chun Qi, Ke An Li, Tong Shen,

Tópico(s)

Glycosylation and Glycoproteins Research

Resumo

Erythrosin B (EB) binding to proteins causes a decrease in the fluorescence maximum of EB at 550 nm. Based on this, a new, fast and simple fluorescence quenching method for the determination of proteins is developed. The linear range of this assay is 1.36–20.4 μg ml−1. The method has very few interferences, most of which can be minimized by dilution. In the detection of proteins in human serum, this method gave values close to that of the Coomassie brilliant blue method.

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