Treatment of cervical dystonia with botulinum toxin
2004; Wiley; Volume: 19; Issue: S8 Linguagem: Inglês
10.1002/mds.20024
ISSN1531-8257
Autores Tópico(s)Hereditary Neurological Disorders
ResumoMovement DisordersVolume 19, Issue S8 p. S109-S115 Research Article Treatment of cervical dystonia with botulinum toxin Joseph Jankovic MD, Corresponding Author Joseph Jankovic MD [email protected] Parkinson's Disease Center and Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine, Houston, Texas, USAParkinson's Disease Center, Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine, 6550 Fannin, 1801, Houston, TX 77030Search for more papers by this author Joseph Jankovic MD, Corresponding Author Joseph Jankovic MD [email protected] Parkinson's Disease Center and Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine, Houston, Texas, USAParkinson's Disease Center, Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine, 6550 Fannin, 1801, Houston, TX 77030Search for more papers by this author First published: 09 March 2004 https://doi.org/10.1002/mds.20024Citations: 90Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Abstract Cervical dystonia (CD) is the most common form of dystonia encountered in a movement disorders clinic. The treatment of this focal dystonia has improved markedly with the advent on botulinum toxin (BTX) injections, which has now become the treatment of choice. Initial studies, even double-blind controlled trials, failed to show robust effect, largely as a result of poor design, often using fixed dosage and site of administration. When the BTX treatment is customized to the needs of the individual patients and the most involved muscles are targeted, the effects can be quite dramatic and the improvement usually lasts 3 to 4 months. Experience and improved skills can largely prevent the adverse effects such as dysphagia and neck weakness. 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