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Value of [ 11 C]choline-Positron Emission Tomography for Re-Staging Prostate Cancer: A Comparison With [ 18 F]fluorodeoxyglucose-Positron Emission Tomography

2003; Lippincott Williams & Wilkins; Volume: 169; Issue: 4 Linguagem: Inglês

10.1097/01.ju.0000056901.95996.43

1527-3792

Maria Picchio, C. Messa, Claudio Landoni, Luigi Gianolli, Sandro Sironi, Marcos Leal Brioschi, Mario Matarrese, Deliu Victor Matei, Francesco De Cobelli, Alessandro Del Maschio, F. Rocco, P. Rigatti, Ferruccio Fazio,

Medical Imaging Techniques and Applications

No AccessJournal of UrologyCLINICAL UROLOGY: Original Articles1 Apr 2003Value of [11C]choline-Positron Emission Tomography for Re-Staging Prostate Cancer: A Comparison With [18F]fluorodeoxyglucose-Positron Emission Tomography M. PICCHIO, C. MESSA, C. LANDONI, L. GIANOLLI, S. SIRONI, M. BRIOSCHI, M. MATARRESE, D.V. MATEI, F. DE COBELLI, A. DEL MASCHIO, F. ROCCO, P. RIGATTI, and F. FAZIO M. PICCHIOM. PICCHIO More articles by this author , C. MESSAC. MESSA More articles by this author , C. LANDONIC. LANDONI More articles by this author , L. GIANOLLIL. GIANOLLI More articles by this author , S. SIRONIS. SIRONI More articles by this author , M. BRIOSCHIM. BRIOSCHI More articles by this author , M. MATARRESEM. MATARRESE More articles by this author , D.V. MATEID.V. MATEI More articles by this author , F. DE COBELLIF. DE COBELLI More articles by this author , A. DEL MASCHIOA. DEL MASCHIO More articles by this author , F. ROCCOF. ROCCO More articles by this author , P. RIGATTIP. RIGATTI More articles by this author , and F. FAZIOF. FAZIO More articles by this author View All Author Informationhttps://doi.org/10.1097/01.ju.0000056901.95996.43AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: We compared [11C]choline-positron emission tomography (PET) with [18F]fluorodeoxyglucose-PET for re-staging prostate cancer in a group of 100 patients. Materials and Methods: A total of 100 consecutive patients referred for whole body [18F]fluorodeoxyglucose-PET for clinical prostate re-staging after radical treatment for prostate cancer were retrospectively included in the study. Mean prostate specific antigen (PSA) was 6.57 ng./ml. In all cases [11C]choline-PET was also performed. PET studies were done with a multiring device 5 minutes after intravenous injection of approximately 370 MBq. [11C]choline and 60 minutes after injection of approximately 370 MBq. [18F]fluorodeoxyglucose. PET findings were compared with those obtained with different conventional imaging and with PSA assessed at the time of PET and 1 year later. Results: Areas of abnormal focal increases were noted in 47% of patients on [11C]choline-PET and in 27% on [18F]fluorodeoxyglucose-PET. Of the 100 patients 49 had positive conventional imaging findings. All except 14 [11C]choline-PET findings were concordant with conventional imaging, including 6 negative and 8 positive conventional imaging results. All except 1 [11C]choline-PET negative cases also had negative conventional imaging after 1 year. PSA at 1 year remained stable or decreased in 80% and 62% of [11C]choline-PET negative and positive cases, respectively. Conclusions: [11C]choline-PET seems to be useful for re-staging prostatectomy cases with increasing serum PSA levels. 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Google Scholar 20 : A combined PET/CT scanner for clinical oncology. J Nucl Med2000; 41: 1369. Google Scholar From the Institute H. San Raffaele, University of Milano-Bicocca, CNR Institute for Molecular Bioimaging and Physiology and Divisions of Urology, European Institute for Oncology and University of Milan, H. San Paolo, Milan, Italy© 2003 by American Urological Association, Inc.FiguresReferencesRelatedDetailsCited byGiovacchini G, Picchio M, Garcia-Parra R, Mapelli P, Briganti A, Montorsi F, Gianolli L and Messa C (2018) [11C]Choline Positron Emission Tomography/Computerized Tomography for Early Detection of Prostate Cancer Recurrence in Patients with Low Increasing Prostate Specific AntigenJournal of Urology, VOL. 189, NO. 1, (105-110), Online publication date: 1-Jan-2013.Mitchell C, Lowe V, Rangel L, Hung J, Kwon E and Karnes R (2018) Operational Characteristics of 11C-Choline Positron Emission Tomography/Computerized Tomography for Prostate Cancer with Biochemical Recurrence After Initial TreatmentJournal of Urology, VOL. 189, NO. 4, (1308-1313), Online publication date: 1-Apr-2013.Giovacchini G, Picchio M, Briganti A, Cozzarini C, Scattoni V, Salonia A, Landoni C, Gianolli L, Di Muzio N, Rigatti P, Montorsi F and Messa C (2018) [11C]Choline Positron Emission Tomography/Computerized Tomography to Restage Prostate Cancer Cases With Biochemical Failure After Radical Prostatectomy and No Disease Evidence on Conventional ImagingJournal of Urology, VOL. 184, NO. 3, (938-943), Online publication date: 1-Sep-2010.Martorana G, Schiavina R, Corti B, Farsad M, Salizzoni E, Brunocilla E, Bertaccini A, Manferrari F, Castellucci P, Fanti S, Canini R, Grigioni W and D’Errico Grigioni A (2018) 11C-Choline Positron Emission Tomography/Computerized Tomography for Tumor Localization of Primary Prostate Cancer in Comparison With 12-Core BiopsyJournal of Urology, VOL. 176, NO. 3, (954-960), Online publication date: 1-Sep-2006. Volume 169Issue 4April 2003Page: 1337-1340 Advertisement Copyright & Permissions© 2003 by American Urological Association, Inc.Keywordsprostatic neoplasmstomography, emission-computedneoplasm stagingprostateprostatectomyMetricsAuthor Information M. PICCHIO More articles by this author C. MESSA More articles by this author C. LANDONI More articles by this author L. GIANOLLI More articles by this author S. SIRONI More articles by this author M. BRIOSCHI More articles by this author M. MATARRESE More articles by this author D.V. MATEI More articles by this author F. DE COBELLI More articles by this author A. DEL MASCHIO More articles by this author F. ROCCO More articles by this author P. RIGATTI More articles by this author F. FAZIO More articles by this author Expand All Advertisement PDF downloadLoading ...