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BIBTEX RIS

Effect of HP-β-cyclodextrin in the diffusion behaviour of hydrocortisone in aqueous solutions at T=298.15K

2012; Elsevier BV; Volume: 441; Issue: 1-2 Linguagem: Inglês

10.1016/j.ijpharm.2012.11.021

ISSN

1873-3476

Autores

Ana C.F. Ribeiro, Luís M.P. Veríssimo, Cecília I. A. V. Santos, Ana M. T. D. P. V. Cabral, Francisco Veiga, Miguel A. Esteso,

Tópico(s)

Surfactants and Colloidal Systems

Resumo

Binary (D) and ternary (D(11), D(22), D(12) and D(21)) mutual diffusion coefficients determined by the Taylor dispersion method are reported for two aqueous systems, pure hydrocortisone (HC/H(2)O) and HC plus HP-β-cyclodextrin (HC/HP-βCD/H(2)O), at T=298.15 K. From these data, some thermodynamic information as well as conclusions about the influence of that carbohydrate in the diffusion of this drug are given.

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