Detection of clenbuterol residues in hair
1994; Royal Society of Chemistry; Volume: 119; Issue: 12 Linguagem: Inglês
10.1039/an9941902663
ISSN1364-5528
AutoresAlbert Adam, Nicole Gervais, A. Panoyan, Huy Ong, Louise Béliveau, Christiane Ayotte, Philippe Delahaut,
Tópico(s)Mass Spectrometry Techniques and Applications
ResumoSixty rats were grown in the presence of 10 (n = 30) and 100 (n = 30) micrograms kg-1 body mass of clenbuterol for a period of 10 d. An immunoextraction step coupled with a competitive enzyme immunoassay allowed the quantification of clenbuterol in hair upon 20 (10 micrograms kg-1) and 30 d (10 micrograms kg-1) after the last dose. This accumulation in hair contrasts with the rapid clearance in tissues. The nature of the immunoreactive material was confirmed by mass spectrometry.
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