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Lymphocyte Apoptosis ‐ Mechanisms and Implications in Disease

1994; Wiley; Volume: 142; Issue: 1 Linguagem: Inglês

10.1111/j.1600-065x.1994.tb00887.x

1600-065X

Sarah Howie, David J. Harrison, Andrew H. Wyllie,

T-cell and B-cell Immunology

Immunological ReviewsVolume 142, Issue 1 p. 141-156 Lymphocyte Apoptosis - Mechanisms and Implications in Disease Sarah E. M. Howie, Corresponding Author Sarah E. M. Howie Cancer Research Campaign Laboratories, Department of Pathology, Edinburgh University Medical School. Teviot Place, Edinburgh EH8 9AG, Scotland.Dr. S. E. M. Howie.Search for more papers by this authorDavid J. Harrison, David J. Harrison Cancer Research Campaign Laboratories, Department of Pathology, Edinburgh University Medical School. Teviot Place, Edinburgh EH8 9AG, Scotland.Search for more papers by this authorAndrew H. Wyllie, Andrew H. Wyllie Cancer Research Campaign Laboratories, Department of Pathology, Edinburgh University Medical School. Teviot Place, Edinburgh EH8 9AG, Scotland.Search for more papers by this author Sarah E. M. Howie, Corresponding Author Sarah E. M. Howie Cancer Research Campaign Laboratories, Department of Pathology, Edinburgh University Medical School. Teviot Place, Edinburgh EH8 9AG, Scotland.Dr. S. E. M. Howie.Search for more papers by this authorDavid J. Harrison, David J. Harrison Cancer Research Campaign Laboratories, Department of Pathology, Edinburgh University Medical School. Teviot Place, Edinburgh EH8 9AG, Scotland.Search for more papers by this authorAndrew H. Wyllie, Andrew H. Wyllie Cancer Research Campaign Laboratories, Department of Pathology, Edinburgh University Medical School. Teviot Place, Edinburgh EH8 9AG, Scotland.Search for more papers by this author First published: December 1994 https://doi.org/10.1111/j.1600-065X.1994.tb00887.xCitations: 28AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat REFERENCES Abbadie, C, Kabrun, N., Bouali, F, Smardova, J., Stehelin, D, Vandenbunder, B. & Enrietto, P. J. (1993) High levels of c-rel expression are associated with programmed cell death in ihe developing avian embryo and in bone marrow cells in vitro. Cell 75, 899. Alam, R., Forsythe, P., Stafford, S. & Fukuda, Y. (1994) Transforming growth factor β abrogates the effects of hematopoietins on eosinophils and induces their apoptosis. J. Exp. Med. 179, 1041. Ameison, J. C. (1992) Programmed cell death and AIDS: from hypothesis to experiment. Immunol. Today 13, 388. Arends, M. J., McGregor, A. H., Toft, N. J., Brown, E. J. & Wyllie, A. H. (1993) Susceptibility to apoptosis is differentially regulated by c-myc and mutated Ha-ras oncogenes and is associated with endonuclease availability. Br. J. Cancer 68, 1127. Arends, M. J. & Wyllie, A. H. (1991) Apoptosis: Mechanisms and Roles in Biology. Int. Rev. Exp. Path. 42, 223. Askew, D. S., Ashmun, R. A., Simmons, B. C. & Cleveland, J. L. (1991) Constitutive c-myc expression in an IL-3 dependent myeloid cell line suppresses cell cycle arrest and accelerates apoptosis. Oncogene 6, 1915. Banda, N. K., Bernier, J., Kurahara, D. K., Kurrle, R., Haigwood, N., Sekaly, R-P & Finkel, T. H. (1992) Crosslinking CD4 by Human Immunodeficiency Virus gpl20 primes T cells for activation-induced apoptosis. J. Exp. Med. 176, 1099. Bellamy, C. O. C, Malcolmson, R. D. G., Harrison, D. J. & Wyllie, A. H. (1995) Cell death in health and disease: the biology and regulation of apoptosis. Seminars in Oncology (in press). Budd, R. C, Cerottini, J-C. & MacDonald, H. R. (1987) Phenotypic identification of memory cytolytic T lympocytes in a subset of Lyt-2 + cells. J. Immunol. 139, 1009. Bursch, W, Paffe, S., Putz, B, Barthel, G. & Schulte-Hermann, R. (1990) Determination of the length of the histological stages of apoptosis in normal liver and in altered hepatic foci of rats. Carcinogenesis 11, 847. Clarke, A. R., Gledhill, S., Hooper, M. L., Bird, C. C. & Wyllie, A. H. (1994) p53 dependence of early apoptotic and proliferative responses within the mouse intestinal epithelium following γ irradiation. Oncogene 9, 1767. Clarke, A. R., Maandag, E. R. van Roon, M., van der Lugt, N. M.J., van der Valk, M., Hooper, M. L. Berns, A. & te Riele, H. (1992) Requirement for a functional Rb-1 gene in murine development. Nature 359, 328. Clarke, A. R., Purdie, C. A., Harrison, D. J., Morris, R. G., Bird, C. C, Hooper, M. L. & Wyllie, A. H. (1993) Thymocyte apoptosis induced by p53-dependent and independent pathways. Nature 362, 849. Cobbold, S. P., Jayasuriya, A., Nash, A., Prospero, T. D. & Waldman, H. (1984) Therapy with monoclonal antibodies by elimination of T cell subsets in vivo. Nature 312, 548. Evan, G. I., Wyllie, A. H., Gilbert, C. S., Littlewood, T. D., Land, H., Brooks, M., Waters, C. M., Penn, L. Z. & Hancock, D. C. (1992) Induction of apoptosis in fibroblasts by c-myc protein. Cell 69, 119. Fauci, A. S. (1988) The human immunodeficiency virus: infectivity and mechnisms of pathogenesis. Science 239, 617. Froebel, K. S., Doherty, K. V, Whitelaw, J. A., Hague, R. A., Mok, J. Y. & Bird, A. G. (1991) Increased expresseion of the CD45RO (memory) antigen on T cells in HIV infected children. AIDS 5, 97. Fyfe, L. J., Maingay, J. P & Howie, S. E.M. (1993) Murine HIV-1 p24 specific T lymphocyte activation by different antigen presenting cells: B lymphocytes from immunized mice present core antigen to T cells. Immunol. Lett. 35, 45. Gavrieli, Y., Sherman, Y. & Ben-Sasson, S. A. (1992) Identification of programmed cell death in situ via specific labelling of nuclear DNA fragmentation. J. Cell Biol 119, 493. Harrison, D. J., Crowe, A. M. & Wyllie, A. H. (1989) Single strand DNA breaks in mitogen stimulated T lymphocytes are religated by a mechanism independent of accessory cells. Clin. Exp. Immunol. 75, 113. Hollstein, M., Sidransky, D., Vogelstein, B. & Harris, C. C. (1991) p53 mutations in human cancers. Science 253, 49. Horneff, G., Guse, A. H., Shulze-Koops, A. H., Kalden, J. R., Burmester, G. R. & Emmrich, E (1993) Human CD4 modulation in vivo induced by antibody treatment. Clin. Immunol. Immunopathol. 66, 80. Howie, S. E. M., Sommerfield, A. J., Gray, E. & Harrison, D. J. (1994) Peripheral T lymphocyte deletion by apoptosis after CD4 ligation in vivo: selective loss of CD44-and "activating" memory T cells. Clin. Exp. Immunol. 95, 195. Johnstone, A. P. (1984) Rejoining of DNA strand breaks is an early event during the stimulation of quiescent lymphocytes. Eur. J. Biochem. 140, 401. Johnstone, A. P. & Williams G. T (1983) DNA strand breaks and differentation. Immunol Today 4, 8. Kastan, M. B., Oneykwere, O., Sidransky, D, Vogelstein, B. & Craig, R. W (1991) Participation of p53 protein in the cellular response to DNA damage. Cancer Res. 51, 6304. Kaufman, S. H., Desnoyers, S., Ottaviano, Y., Davidson, N. E. & Poirer, G. G. (1993) Specific proteolytic cleavage of poly(ADP ribose) polymerase: an early marker of chemotherapy induced apoptosis Cancer Res. 53, 3976. Kerr, J. E R., Wyllie, A. H. & Currie, A. R. (1972) Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer 26, 239. Kumar, S., Kinoshita, M., Noda, M., Copeland, N. G. & Jenkins, N. A. (1994). Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1β-converting enzyme. Genes. Devel 8, 1613. Lane, D. P. (1992) p53, guardian of the genome. Nature 358, 15. Levine, A. J., Momand, J. & Finlay, C. A. (1991) The p53 tumour suppressor gene. Nature 351, 453. Lowe, S. W. Schmitt, E. M., Smith, S. W, Osborne, B. A. & Jacks, T (1993) p53 is required for radiation induced apoptosis in mouse thymocytes. Nature 362, 847. Lubbert, M., Miller, C. W, Kahan, J. & Koeffler, P. (1989) Expression, methylation and chromatin structure of the p53 gene in untransformed and human T-cell leukaemia virus transformed human T lymphocytes, Oncogene 4, 643. MacLennan, L. CM. & Chan, E. (1993) The dynamic relationship between B cell populations in adults. Immunology Today 14, 29. Micdema, F., Tersmette, M. & van Lier, R. A. W. (1990) AIDS Pathogenesis: a dynamic interaction between HIV and the immune system. Immunology Today 11, 293. Miura, M., Zhu, H., Rotello, R., Hartwieg, E. A. & Yuan, J. (1993) Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog or the C. elegans death gene ced-3. Cell 75, 653. Newell, M. K., Haughn, L. J., Maroun, Y. & Julius, M. H. (1990) Death of mature T cells by separate ligation of CD4 and the T cell receptor for antigen. Nature 347, 286. Ogasawara, J., Watanabe-Fukunaga, R., Adachi, M., Matsuzawa, A., Kasugai, T., Kitamura. Y, Itoh, N., Suda, T. & Nagata, S. (1993) Lethal effect of the anti-Fas antibody in mice. Nature 364, 806. [Erratum in Nature 365, 568]. Opipari, A. J., Hu, H. M., Yabkowitz, R. & Dixit, V. M. (1992) The A20 zinc finger protein protects cells from tumor necrosis factor cytotoxicity. J. Biol Chem- 267, 12424. Owen, R. J., Musk, R, Evans, C. A. & Whetton, D. (1993) Cellular signalling events elicited by v-abl associated with growth factor independence in an interleukin-3-dependent eel line. J. Biol. Chem. 268, 15696. Purdie, C. A., Harrison, D. J., Peter, A., Dobbie, L., White, S., Howie, S. E.M., Salter, D. M., Bird, C. C, Wyllie, A. H., Hooper, M. L. & Clarke A. R. (1994) Tumor incidence, spectrum and ploidy in mice with a large deletion in the p53 gene. Oncogene 9, 603. Qin, S., Cobbold, S. R, Tighe, H., Benjamin, R. & Waldmann, H. (1987) CD4 monoclonal antibody pairs for immunosuppression and tolerance induction. Eur. J. Immunol. 17, 1159. Reed, J. C, Alper, J. D., Nowell, R. C- & Hoover, R. G. (1986) Sequential expression of protooncogenes during lectin-stimulated mitogenesis of normal human lymphocytes. Proc. Natl. Acad. Sci. (USA) 83, 3982. Russell, J. H., Rush, B., Weaver, C. & Wang, R. (1993) Mature T cells of autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide, Proc. Natl. Acad Sci. (USA) 90, 4409. Ryan, J. J., Danish, R., Gottlieb, C. A. & Clarke, M. F. (1993) Cell cycle ananysis of p53-induced cell death in murine erythroleukaemia cells. Mol Cell. Biol. 13, 711. Savill, J., Fadok, V. Henson, P & Haslett, C. (1993) Phagocyte recognition of cells undergoing apotosis. Immunol. Today 14, 131. Savill, J., Wyllie, A. H., Henson, J. E., Walport, M. J., Henson, P. M. & Haslett, C. (1989) Macrophage phagocytosis of aging neutrophils in inflammation. J. Clin. Invest. 83, 865. Squier, M. K.T. & Cohen, J. J. (1994) Cell-mediated cytotoxic mechanisms. Curr. Op. Immunol. 6, 447. Troppmair, J., Cleveland, J. L., Askew, D. S. & Rapp, U. R. (1992) v-raf/v-myc synergism in abrogation of IL-3 dependence: v-raf suppresses apoptosis, Curr. Top. Microbiol. Immunol. 182, 453. Ucker, D. S., Obermiller, P. S., Eekhart, W., Apgar, J. R., Berger, N. A, & Meyers, J. (1992) Genome digeston is a dispensable consequence of physiological cell death mediated by cytotoxic T lymphocytes. Mot. Cell. Biol. 12, 3060. Vogelstein, B. (1990) A deadly inheritence. Nature 348, 681. White, E. (1993) Regulation of apoptosis by the transforming genes of the DNA tumor virus Adenovirus- Proc. Soc. Exp. Med. Biot. 254, 30. Wijsman, J. H., Jonker, R. J., Keijzer, R., van de Velde, C. J. H, Cornelisse, C. J. & van Dierendonck, J. H. (1993) A new method to detect apoptosis in paraffin sections: in situ end labelling of fragmented DNA. J. Histochem. Cytochem. 41, 7. Wu, X. & Levine, A. J. (1994) p53 and E2E-1 cooperate lo moderate apoptosis. Proc. Natl. Acad. Sci. (USA) 91, 3602. Wyllie, A. H. (1980) Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 288, 555. Wyllie, A. H. (1987) Apoptosis: cell death in tissue regulation. J. Pathol. 153, 313. Wyllie, A. H. (1988) Apoptosis; ISI Atlas Sci: Immunol. 1, 192. Wyllie, A. H. (1992) Apoptosis and the regulation of cell numbers. Cancer Metast Rev 11, 95. Wyllie, A. H. (1994) Apoptosis: death gets a brake. Nature 369, 272. Citing Literature Volume142, Issue1December 1994Pages 141-156 ReferencesRelatedInformation