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Solid‐Phase Synthesis of Glycopeptide Amides under Mild Conditions: Morphiceptin Analogues

1990; Wiley; Volume: 29; Issue: 3 Linguagem: Inglês

10.1002/anie.199002911

1521-3773

Eduard Bardajı́, Josep Lluı́s Torres, Pere Clapés, Fernando Alberício, George Bárány, Gregorio Valencia,

Glycosylation and Glycoproteins Research

Membrane glycoproteins belong to the most important compounds in living nature. The glycoprotein amides (morphiceptin analogous) have now become readily accessible by a solid-phase method (glycosyl is galacto- or glucopyranosyl). Upon detachment from the carrier, the sensitive glycosidic bond remains intact.