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Effect of genetic polymorphism of CYP2C19 on eradication of Helicobacter pylori with various triple therapies

2001; Elsevier BV; Volume: 120; Issue: 5 Linguagem: Inglês

10.1016/s0016-5085(08)82920-4

1528-0012

Yutaka Yamaji, Yoshihiro Hirata, Masao Akanuma, Yuzo Mitsuno, Shin Maeda, Keiji Ogura, Makoto Okamoto, Haruhiko Yoshida, Takao Kawabe, Yasushi Shiratori, Masao Omata,

Gastroesophageal reflux and treatments

was good intra-laboratory correlation (91% agreement within 2 log2 by AD and 90% by ET), and there were 8 very major errors from 3 centers and 5 major errors (S reported as R) from 2 centers, Overall for MTZ 88% of AD versus ET results were within 2 log2 dilutions.Conclusion: This study indicates that use of a standardized prococol based on NCCLS guidelines facilitates identification of CLA and MTZ susceptible and resistant strains of H. pylofi using either AD or ET methods.