Hepatitis B vaccination in a hyper-endemic tribal community from India: assessment after three years
2004; Elsevier BV; Volume: 23; Issue: 3 Linguagem: Inglês
10.1016/j.vaccine.2004.05.038
ISSN1873-2518
AutoresManoj Murhekar, Kanchan Murhekar, S C Sehgal,
Tópico(s)Hepatitis C virus research
ResumoHepatitis B infection is highly endemic among the primitive tribes of Andaman and Nicobar Islands, India and it is necessary to initiate hepatitis B vaccination for control of this infection. A pilot project of mass hepatitis B vaccination using indigenously developed vaccine was initiated among Nicobarese tribe of Car Nicobar Island. Sero-protection rates after second and third year were 89% and 85.5%, respectively. The rate of chronic infection in the vaccinated population after three years was 1.86% compared to the pre-vaccination rate of 20.7%. Considering high sero-protection rates and low cost, the indigenous vaccine could be used for vaccination programme in this tribal community.
Referência(s)