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Artigo Revisado por pares
BIBTEX RIS

Potent α-ketocarbonyl and boronic ester derived inhibitors of proteasome

1996; Elsevier BV; Volume: 6; Issue: 3 Linguagem: Inglês

10.1016/0960-894x(96)00014-5

ISSN

1464-3405

Autores

Mohamed Iqbal, Sankar Chatterjee, James C. Kauer, John P. Mallamo, Patricia A. Messina, Alyssa Reiboldt, Robert Siman,

Tópico(s)

Endoplasmic Reticulum Stress and Disease

Resumo

Potent and selective α-ketocarbonyl (8a–b) and boronic ester (11) derived inhibitors of the chymotrypsin-like activity of proteasome, first member of a newly identified class of threonine proteases, are described.

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