Light-induced transformations of hematoporphyrin diacetate and hematoporphyrin
1988; Elsevier BV; Volume: 2; Issue: 3 Linguagem: Inglês
10.1016/1011-1344(88)85056-5
ISSN1873-2682
AutoresJurgita Rotomskien≐, Rūta Kapočiūt≐, Ričardas Rotomskis, Gediminas Jonušauskas, Tatiana Szitó, Alexandr Nizhnik,
Tópico(s)Nanoplatforms for cancer theranostics
ResumoIllumination of hematoporphyrin diacetate (HP-Diac) and hematoporphyrin (HP) in phosphate-buffered solutions causes the formation of a stable photoproduct absorbing at 636 nm. Simultaneously the photo-oxidation of HP-Diac and HP takes place. These phototransformations depend on the illumination dose and the concentration of the HP-Diac or HP solution, and cause qualitatively the same spectral changes independently of the light source used.
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