Gold-Catalyzed Oxidative Coupling Reactions with Aryltrimethylsilanes
2010; American Chemical Society; Volume: 12; Issue: 21 Linguagem: Inglês
10.1021/ol102194c
ISSN1523-7060
AutoresWilliam E. Brenzovich, Jean-François Brazeau, F. Dean Toste,
Tópico(s)Catalytic C–H Functionalization Methods
ResumoDuring continuing studies with a novel oxidative gold oxyarylation reaction, arylsilanes were found to be competent coupling partners, providing further evidence for an intramolecular electrophilic aromatic substitution mechanism. While providing yields complementary to those of the previously described boronic acid methods, the use of trimethylsilanes reduces the observation of homocoupling byproducts and allows for facile intramolecular coupling reactions.
Referência(s)