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Vitiligo and Juvenile Diabetes Mellitus

1977; American Medical Association; Volume: 113; Issue: 11 Linguagem: Inglês

10.1001/archderm.1977.01640110035002

1538-3652

Chamel Macaron,

Atherosclerosis and Cardiovascular Diseases

• Five juvenile diabetics had vitiligo. In two children, the vitiligo preceded the onset of diabetes. Four of the five patients had thyroid, adrenal, or gastric antibodies or a combination of these. In three children HLA-B8 antigens were detected, and one additional patient had HLA-Bw15. Of eight nondiabetic children with vitiligo, one had abnormal glucose tolerance. To the evidence supporting an autoimmune form of diabetes mellitus we add another observation: the association of insulindependent diabetes and childhood vitiligo. ( Arch Dermatol 113:1515-1517, 1977)