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Significant ecological impact on the progression of fluoroquinolone resistance in Escherichia coli with increased community use of moxifloxacin, levofloxacin and amoxicillin/clavulanic acid

2010; Oxford University Press; Volume: 66; Issue: 3 Linguagem: Inglês

10.1093/jac/dkq471

1460-2091

Óscar Cuevas, Jesús Oteo, Ester Lázaro, Belén Aracil, Francisco J. de Abajo, Silvia García-Cobos, Adriana Ortega, José Campos, D. Fontanals, Elena Loza, Fernando Baquero, Pedro J. J. Alvarez, V. Pulian, Marta García‐Campello, Catia Chaia de Miranda, M. D. Rojo, Pilar López, G. Royo, Pilar Berdonces, Francisco José Vasallo-Vidal, I. Wilhemi, Alberto Delgado‐Iribarren, María Ángeles Mantecón-Vallejo, E. Ojeda, María Teresa Pérez-Pomata, Alicia González, A. Fleites, J Lite, Ma Fe Brezmes, J. Martín Rodríguez, Susana Sabater, Rafael Cantón, Benjamín Fernández‐Gutiérrez, Almudena Tinajas, V. Garcia-Lopez, A Pinedo, Mar Olga Pérez-Moreno, I. Buj, Jorge Calvo, L. Martinez, O. del Valle, M.J Gastañares, Elena Martín, Samuel Bernal, Natalia Montiel, M. D. Crespo, J. J. Palomar, L. Lolli. Marco, María José Revillo, Susana García de Cruz, Cornel Aldea, Alexandre Rosa Campos, P. Teno, M. T. Cabezas, Carmen Raya, Carme Fuster, Nieves Gonzalo, Juan Carlos Alados, Isabel Cuesta, P. Peña, Alberto Yagüe, A. Sierra, Marco Antônio Lemos Miguel, Carmen Aspíroz, E. Garduño, Carmen Amores-Antequera, C. Freyre, Marta Caparrà s Rodriguez, José Antonio Lepe, M. Menéndez-Rivas, María José González-Abad, V. Gallardo,

Antibiotics Pharmacokinetics and Efficacy

ObjectivesTo determine trends in ciprofloxacin resistance and co-resistance to other antibiotic classes in blood isolates of Escherichia coli, and to investigate if there is an ecological relationship to the community use of fluoroquinolones and other antibiotics.