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Capillary column ammonia chemical ionization mass spectrometry of organophosphorus chemical warfare agents and simulants

1986; Wiley; Volume: 13; Issue: 5 Linguagem: Inglês

10.1002/bms.1200130505

2376-3876

Paul A. D’Agostino, L.R. Provost,

Pesticide Exposure and Toxicity

Biomedical & Environmental Mass SpectrometryVolume 13, Issue 5 p. 231-236 Article Capillary column ammonia chemical ionization mass spectrometry of organophosphorus chemical warfare agents and simulants Paul A. D'Agostino, Paul A. D'Agostino Defence Research Establishment Suffield, Ralston, Alberta T0J 2N0, CanadaSearch for more papers by this authorLionel R. Provost, Lionel R. Provost Defence Research Establishment Suffield, Ralston, Alberta T0J 2N0, CanadaSearch for more papers by this author Paul A. D'Agostino, Paul A. D'Agostino Defence Research Establishment Suffield, Ralston, Alberta T0J 2N0, CanadaSearch for more papers by this authorLionel R. Provost, Lionel R. Provost Defence Research Establishment Suffield, Ralston, Alberta T0J 2N0, CanadaSearch for more papers by this author First published: May 1986 https://doi.org/10.1002/bms.1200130505Citations: 34 Defence Research Establishment Suffield, Ralston, Alberta T0J 2N0, Canada AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Abstract Capillary column ammonia chemical ionization mass spectrometry was investigated as a technique for the characterization of a number of organophosphorus chemical warfare agents and simulants, since electron impact ionization provides little or no molecular ion information for these compounds. The effects of source temperature, source pressure, electron energy and electron emission were investigated in order to optimize ammonia chemical ionization conditions. Source temperature was found to have a dramatic effect on the chemical ionization mass spectra acquired. Abundant [M + NH4]+ and/or [M + H]+ quasimolecular ions were usually observed at lower source temperatures for the selected compounds under positive ion chemical ionization conditions, along with a number of characteristic fragmentation ions. Full-scan mass spectra were obtained for 1--2 ng of analyte during the capillary column ammonia chemical ionization operation. The sensitivity, molecular ion information afforded and lack of background interference ions associated with this technique make it a good candidate for the confirmation of organophosphorus chemical warfare agents and simulants. Citing Literature Volume13, Issue5May 1986Pages 231-236 RelatedInformation