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Isolation and characterization of fatty acid binding protein in the liver of the nurse shark, Ginglymostoma cirratum

1991; Elsevier BV; Volume: 98; Issue: 2 Linguagem: Inglês

10.1016/0300-9629(91)90547-p

0300-9629

N M Bass, Joan A. Manning, C.A. Luer,

Influenza Virus Research Studies

1. A 14.5 kDa fatty acid binding protein was isolated from the liver of the nurse shark, Ginglymostoma cirratum. 2. Purified shark liver FABP (pI = 5.4) bound oleic acid at a single site with an affinity similar to that of mammalian FABP. 3. The apparent size, pI and amino acid composition of shark liver FABP indicate a close structural relationship between this protein and mammalian heart FABP.