Predicting Non-Sentinel Lymph Node Status in Breast Cancer Patients with Sentinel Lymph Node Involvement: Evaluation of Two Scoring Systems
2010; Wiley; Volume: 16; Issue: 2 Linguagem: Inglês
10.1111/j.1524-4741.2009.00892.x
ISSN1524-4741
AutoresÁlex Sanjuán, Geòrgia Escaramís, Sergi Vidal‐Sicart, M. Illa, Gabriel Zanón, Jaume Pahisa, S. Rubí, Martín Velasco, Gorane Santamaría, B. Farrús, Montse Muñoz, Yolanda García García, Pedro L. Fernández, Françesca Pons,
Tópico(s)Cancer Risks and Factors
ResumoThe Breast JournalVolume 16, Issue 2 p. 134-140 Predicting Non-Sentinel Lymph Node Status in Breast Cancer Patients with Sentinel Lymph Node Involvement: Evaluation of Two Scoring Systems Alex Sanjuán MD, PhD, Alex Sanjuán MD, PhD Department of Gynecology & Obstetrics, Hospital Clínic, University of Barcelona, SpainSearch for more papers by this authorGeorgia Escaramís PhD, Georgia Escaramís PhD Department of Public Health, University of Barcelona. SpainSearch for more papers by this authorSergi Vidal-Sicart MD, PhD, Sergi Vidal-Sicart MD, PhD Departments of Nuclear MedicineSearch for more papers by this authorMiriam Illa MD, Miriam Illa MD Department of Gynecology & Obstetrics, Hospital Clínic, University of Barcelona, SpainSearch for more papers by this authorGabriel Zanón MD, Gabriel Zanón MD Department of Gynecology & Obstetrics, Hospital Clínic, University of Barcelona, SpainSearch for more papers by this authorJaume Pahisa MD, PhD, Jaume Pahisa MD, PhD Department of Gynecology & Obstetrics, Hospital Clínic, University of Barcelona, SpainSearch for more papers by this authorSebastià Rubí MD, Sebastià Rubí MD Departments of Nuclear MedicineSearch for more papers by this authorMartín Velasco MD, PhD, Martín Velasco MD, PhD RadiologySearch for more papers by this authorGorane Santamaría MD, PhD, Gorane Santamaría MD, PhD RadiologySearch for more papers by this authorBlanca Farrús MD, PhD, Blanca Farrús MD, PhD Radiation OncologySearch for more papers by this authorMontse Muñoz MD, PhD, Montse Muñoz MD, PhD Medical OncologySearch for more papers by this authorYolanda García MD, Yolanda García MD Medical OncologySearch for more papers by this authorPedro Luís Fernández MD, PhD, Pedro Luís Fernández MD, PhD Pathology, Hospital Clínic, University of Barcelona, Barcelona, SpainSearch for more papers by this authorFrancesca Pons MD, PhD, Francesca Pons MD, PhD Departments of Nuclear MedicineSearch for more papers by this author Alex Sanjuán MD, PhD, Alex Sanjuán MD, PhD Department of Gynecology & Obstetrics, Hospital Clínic, University of Barcelona, SpainSearch for more papers by this authorGeorgia Escaramís PhD, Georgia Escaramís PhD Department of Public Health, University of Barcelona. SpainSearch for more papers by this authorSergi Vidal-Sicart MD, PhD, Sergi Vidal-Sicart MD, PhD Departments of Nuclear MedicineSearch for more papers by this authorMiriam Illa MD, Miriam Illa MD Department of Gynecology & Obstetrics, Hospital Clínic, University of Barcelona, SpainSearch for more papers by this authorGabriel Zanón MD, Gabriel Zanón MD Department of Gynecology & Obstetrics, Hospital Clínic, University of Barcelona, SpainSearch for more papers by this authorJaume Pahisa MD, PhD, Jaume Pahisa MD, PhD Department of Gynecology & Obstetrics, Hospital Clínic, University of Barcelona, SpainSearch for more papers by this authorSebastià Rubí MD, Sebastià Rubí MD Departments of Nuclear MedicineSearch for more papers by this authorMartín Velasco MD, PhD, Martín Velasco MD, PhD RadiologySearch for more papers by this authorGorane Santamaría MD, PhD, Gorane Santamaría MD, PhD RadiologySearch for more papers by this authorBlanca Farrús MD, PhD, Blanca Farrús MD, PhD Radiation OncologySearch for more papers by this authorMontse Muñoz MD, PhD, Montse Muñoz MD, PhD Medical OncologySearch for more papers by this authorYolanda García MD, Yolanda García MD Medical OncologySearch for more papers by this authorPedro Luís Fernández MD, PhD, Pedro Luís Fernández MD, PhD Pathology, Hospital Clínic, University of Barcelona, Barcelona, SpainSearch for more papers by this authorFrancesca Pons MD, PhD, Francesca Pons MD, PhD Departments of Nuclear MedicineSearch for more papers by this author First published: 12 March 2010 https://doi.org/10.1111/j.1524-4741.2009.00892.xCitations: 17 Address correspondence and reprint requests to: Alex Sanjuán, MD, PhD, Hospital Clínic Provincial, Villarroel 170, 08036-Barcelona, Spain, or e-mail: [email protected]. Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Abstract Abstract: The aim of this study was to validate a nomogram and a scoring system to predict non-sentinel lymph node status in breast cancer patients with sentinel lymph node (SLN) involvement. A total of 516 breast cancer patients underwent sentinel lymph node biopsy at our institution from January 2001 to August 2006. A prospective database was used to identify breast cancer patients with a positive SLN biopsy examination who underwent a completion axillary lymph node dissection. A total of 114 patients were identified. The Memorial Sloan-Kettering Cancer Center (MSKCC) nomogram and an axilla scoring system from Paris (Hôpital Tenon) were used to predict the probability of having non-SLN involvement. One hundred fourteen patients were included in the study. The areas under the receiver operating characteristics (ROC) curves were 0.671 (95% CI: 0.552–0.790) for the MSKCC nomogram and 0.703 (95% CI: 0.596–0.811) for the Tenon score. The univariate analysis shows that size of SLN metastases, the number of positive and negative SLN and the proportion of positive SLN were statistically significant. On multivariate logistic regression analysis, the size of SLN metastases and the proportion of positive SLN were statistically significant. The two scoring systems are similar according to their area under ROC curves, but should be improved to be valid and determinant to the general population. Meanwhile, the use of scoring systems could be applied in an individual manner in some patients. Citing Literature Volume16, Issue2March/April 2010Pages 134-140 RelatedInformation
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