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Spinal Cord Compression in Prostate Cancer. A 10‐year Experience

1992; Wiley; Volume: 69; Issue: 5 Linguagem: Inglês

10.1111/j.1464-410x.1992.tb15603.x

1365-2176

Mark Rosenthal, David Rosen, Derek Raghavan, J Leicester, P Duval, Michael Besser, Bruce Pearson,

Brain Metastases and Treatment

Of 478 patients treated at a single institution for prostate cancer, 29 developed spinal cord or cauda equina compression. In 5 patients, spinal cord compression was the first evidence of malignancy. Clinical features were predominantly pain, weakness, sensory and sphincter disturbance. The median duration of symptoms was 2 weeks, although the diagnosis was made rapidly at presentation. Clinical diagnosis correlated well with myelographic findings. Only 1 patient suffered neurological deterioration as a consequence of myelography. The functional outcome was dependent on the ability to walk prior to treatment. The median survival in those who were bedridden following treatment was 6 weeks (range 3.5-13) and 21 weeks (range 7-110+) in those who were ambulant following therapy.