Voltar
Artigo Acesso aberto Revisado por pares
BIBTEX RIS

A comparative trial of controlled-onset, extended-release verapamil, enalapril, and losartan on blood pressure and heart rate changes

2002; Oxford University Press; Volume: 15; Issue: 1 Linguagem: Inglês

10.1016/s0895-7061(01)02254-3

ISSN

1941-7225

Autores

George L. Bakris, Domenic Sica, Venkata Ram, Timothy Fagan, P. T. Vaitkus, Robert J. Anders,

Tópico(s)

Cardiovascular Syncope and Autonomic Disorders

Resumo

Background:The excess morning risk of myocardial infarction and stroke may be attributable to the rapid rise in blood pressure (BP) and heart rate in the hours after awakening. The aim of this randomized, double-blinded, placebo-controlled, multicenter study was to compare once-daily, controlled-onset, extended-release (COER-24) verapamil to enalapril and losartan on BP and heart rate during the postawakening morning phase as well as throughout the 24-h period.

Referência(s)