Portal de Periódicos da CAPES

Thalidomide therapy for recalcitrant systemic onset juvenile rheumatoid arthritis

2002; Elsevier BV; Volume: 140; Issue: 1 Linguagem: Inglês

10.1067/mpd.2002.120835

1097-6833

Thomas Lehman, Kim H. Striegel, Karen Onel,

Systemic Lupus Erythematosus Research

Systemic onset juvenile rheumatoid arthritis unresponsive to nonsteroidal anti-inflammatory drugs may be controlled with corticosteroids, but these drugs have significant side effects. We report 2 steroid-dependent children with systemic onset juvenile rheumatoid arthritis who did not respond to multiple nonsteroidal anti-inflammatory drugs, methotrexate, azathioprine, cyclosporine, and etanercept. Both children had significant improvement with thalidomide therapy. (J Pediatr 2002;140:125-7)